Arteta's men know they must win almost every game between now and the end of the season if they are to wrestle Liverpool off the top of the league. Without the likes of Bukayo Saka and Kai Havertz, that may prove difficult.
Saka has been missing since before Christmas, with Gabriel Martinelli and Havertz following him by suffering hamstring problems. Those three players, who would all start if fit for Arsenal at Leicester, are joined by Gabriel Jesus in the treatment room.
Fortunately, there is better news at the back with almost every player available. Takehiro Tomiyau's long-term absence continues but Ben White has returned to training to bolster Arteta's options in the backline.
Academy stars Khayon Edwards and Nathan Butler-Oyedeji are likely to be part of the matchday squad alongside Myles Lewis-Skelly and Ethan Nwaneri.
Whatever happens, the north Londoners should have more than enough to defeat Leicester. The Foxes are staring relegation in the face under Ruud van Nistelrooy and haven't won at home since the start of December. Here, football.london predicts the group that travels to the Midlands.
Arsenal's travelling squad to face Leicester City
Goalkeepers: David Raya, Neto
Defenders: Jurrien Timber, Riccardo Calafiori, Oleksandr Zinchenko, William Saliba, Gabriel Magalhaes, Jakub Kiwior, Myles Lewis-Skelly.
Midfielders: Martin Odegaard (capt), Jorginho, Thomas Partey, Mikel Merino, Declan Rice, Ethan Nwaneri.
Attackers: Raheem Sterling, Leandro Trossard, Leandro Trossard, Khayon Edwards, Nathan Butler-Oyedeji.
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